Maladies attributed to myxomatous mitral valve.

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چکیده

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The myxomatous mitral valve and sudden death.

The clincopathologic features of 14 cases of sudden death attributable to dysrhythmias associated with the myxomatous mitral valve are described. The patients were 14-59 years old (mean 27 +/- 11 years). Eleven were female and three male. Of the seven ECGs available, none showed prolongation of the QT interval, but two showed repolarization abnormalities. The material was classified according t...

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Myxomatous Mitral Valve Disease in Dogs - an Update and Perspectives

When discussing myxomatous valve disease in dogs, one has in mind atrioventricular valves, in particular the mitral valve, which is affected the most commonly and followed by the tricuspid, aortic valve and pulmonic valve, the last being seldom degenerated. Myxomatous mitral valve disease (MVD) is the most common cause of heart failure in dogs (1). In literature it can be found under various na...

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Molecular changes in fibrillar collagen in myxomatous mitral valve disease.

INTRODUCTION Myxomatous mitral valve disease (MMVD) is the single most common acquired cardiac disease of dogs and is a disease of significant veterinary importance. It also bears close similarities to mitral valve prolapse in humans and therefore is a disease of emerging comparative interest. We have previously mapped the structure of collagen fibrils in valve leaflets using synchrotron X-rays...

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Developmental basis for filamin-A-associated myxomatous mitral valve disease.

AIMS We hypothesized that the structure and function of the mature valves is largely dependent upon how these tissues are built during development, and defects in how the valves are built can lead to the pathological progression of a disease phenotype. Thus, we sought to uncover potential developmental origins and mechanistic underpinnings causal to myxomatous mitral valve disease. We focus on ...

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Myxomatous Mitral Valve with Prolapse and Flail Scallop

BACKGROUND Myxomatous mitral valve with prolapse are classically seen with abnormal leaflet apposition during contraction of the heart. Hemodynamic disorders can result from eccentric mitral regurgitation usually caused by chordae tendinae rupture or papillary muscle dysfunction. Echocardiography is the gold standard for evaluation of leaflet flail and prolapse due to high sensitivity and speci...

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ژورنال

عنوان ژورنال: Circulation

سال: 1991

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.83.1.328